Stem cell transplantation, a promising direction for regenerative medicine, benefits from a means of tracking these cells over an extended period. Transduction of reporter genes into cells remains popular, but is labour and time intensive.
Presented herein is the labelling and monitoring of adipose tissue-derived stem cells for up to 42 days after transplantation with a bio-compatible, 30-nm Cellaris™ 670 (Luminicell) nano-particulate fluorescent probe.
The solution is characterized by its exceptional brightness, photo-stability and resilience against various biological processes, ultimately yielding strong signal longevity. The extended duration of its tracking ability is unprecedented, compared with other exogeneous fluorophores, which represents a leap forward in simple stem-cell monitoring, unveiling its potential in other applications.
Read the full application note here (available in English and Simplified Chinese):