Aggregation-Induced Emission Fluorescence Nanoparticles 

Luminicell’s proprietary aggregation-induced emission (AIE) fluorescence nanoparticles are excellent biocompatible lipid nanoparticles comes with encapsulated AIE dyes. These AIE fluorescence nanoparticles are non-toxic to cells, extremely bright, highly resistance to photobleaching effect, rendering them the ideal probe for long-term imaging.

Aggregation-Induced Emission (AIE)

AIE materials exhibit strong fluorescence upon self-assembly or aggregation. Our current product portfolio consists of fluorescence labels across the visible (blue, green, red) and NIR spectral region, compatible for both single-photon and two-photon fluorescence microscopy.

Biocompatible and Uniform Encapsulation Matrix 

Our Luminicell Trackers consist of AIE materials that are well-encapsulated with an amphiphilic lipid polymer matrix. The encapsulation matrix is highly biocompatible with negligible toxicity effect on cells, where the AIE dyes are now densely packed in highly uniform lipid nanoparticles, allowing the aggregated AIE to exhibit their unique properties. 

Functionalised Surface for Targeting Ability

Different targeting groups and functional moieties can be made readily available on the surface of our AIE fluorescence lipid nanoparticles, providing great convenience and ease of conjugation to antibodies or peptides of interest. These functional groups can be used for conjugation such as Thiol-maleimide reaction, as well as Clickable alkyne and azide groups.

Product Validation

Luminicell Tracker are formulated with our proprietary AIEdots technology, and have been applied across different applications, for instances: long-term live cell tracking, deep tissue bioimaging, which includes intravital vascular tracking and diagnostic immunoassays. Refer to references for a list of publications with Luminicell dyes and latest application notes.

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